The American Academy of Dermatology (AAD) has published comprehensive updated guidelines for the treatment of acne vulgaris in adults, reflecting new evidence on hormonal therapies, biologics, and combination approaches.

Key Updates

The new guidelines emphasize earlier use of hormonal therapies in adult women with acne, expanded recommendations for spironolactone, and updated guidance on isotretinoin monitoring protocols.

Hormonal Therapy Recommendations

For adult women with inflammatory acne, the guidelines now recommend considering spironolactone as a first-line systemic option alongside traditional therapies, citing growing evidence of its efficacy and safety profile.

Combination Therapy

The guidelines reinforce the importance of combination therapy approaches, recommending concurrent use of topical retinoids with either benzoyl peroxide or topical antibiotics for optimal outcomes.